ADVICE ON CORRECT ADMINISTRATION

Disinfection procedure:

The applicator must be cleaned and disinfected in a non-irritating antiseptic solution before and after use and between each animal.

Applicator method of use and Insertion:

Bend the device before inserting in the applicator. Ensure the string is in the appropriate slot.

Lightly lubricate the distal end of the applicator with an obstetrical lubricant.

Clean the animal’s vulva before gently inserting the applicator in the vagina.

Once the applicator has reached the fundus of the vagina, press on the handle to release the device.

Remove the applicator gently and ensure the string is outside the vulva. Shorten the string according to animal’s size if necessary.

Removal:

Remove 7 days after insertion by gently pulling on the exposed string.

Timing of insemination:

Animals should be inseminated 56 hours after removal of the device.

SPECIAL WARNINGS

The progesterone treatment alone, according to dosage regimen proposed, is not sufficient to induce oestrus and ovulation in all cycling females.

In order to optimise the protocol, it is advisable to determine cycling ovarian activity before using the progesterone treatment.

Animals in poor condition, whether from illness, inadequate nutrition, or other factors, may respond poorly to treatment.

Precautions for use in animals

It is recommended to wait a minimum of 35 days following parturition before starting the treatment with this product.

Special precautions to be taken by the person administering the medicinal product to the animals

Gloves must be worn when handling the product both during insertion and removal.

Do not eat or drink when handling the product.

Wash hands after use.

Use during pregnancy and lactation

Can be used during lactation.

Do not use before 35 days have passed since previous calving.

Laboratory studies in rat and rabbit, after intramuscular or subcutaneous administrations, and at repeated high doses of progesterone, have produced evidence of foetotoxic effects. The use of the product is contra indicated in pregnant cattle.

Interactions, Incompatibilities

None known.

Overdose

Not applicable.